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Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure

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virtual clinical :: Article Creator The Virtual Body That Could Make Clinical Trials Unnecessary Developing new drugs and treatments is expensive, both in terms of cost as well as time. But a virtual human body could eventually make computerized clinical trials the norm, saving time and money and keeping real human bodies out of harm's way. The Virtual Physiological Human (VPH) Institute in Europe is working to create a digital model of the human body for in silico, or computer-based, research and clinical trials. "We want to use computer models that are based on physiology to provide a tool to clinicians, doctors, and researchers in medicine to provide better health care," said Liesbet Geris, executive director of the VPH Institute. According to Geris, healthcare-related big data makes a holistic view of the human body available to doctors and researchers exploring the best treatment plans for their patients. The benefits of in ...

Even low doses of steroids increase the risk of cardiovascular disease in people with inflammatory diseases

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clinical phase 1 :: Article Creator Phase 1/2 Trial Will Test Cell Therapy Rese-cel In Relapsing, Progressive MS Cabaletta Bio is getting set to launch a clinical trial testing its cell therapy resecabtagene autoleucel (rese-cel) in people with relapsing and progressive forms of multiple sclerosis (MS). The company sought permission last year from the U.S. Food and Drug Administration (FDA) to start the study. Once such an application is submitted, the FDA has 30 days to review it for any safety issues. That 30-day window has elapsed, meaning Cabaletta can proceed with its study. "We look forward to building on our momentum as we move closer to realizing our vision of launching the first targeted curative cell therapy designed specifically for patients with autoimmune disease," Steven Nichtberger, MD, CEO of Cabaletta, said in a company press release. In MS, an inflammatory attack damages healthy parts of the brain and spinal cord,...

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets

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explain coronary artery disease :: Article Creator Coronary Artery Disease Coronary artery disease (CAD; also atherosclerotic heart disease) is the end result of the accumulation of atheromatous plaques within the walls of the coronary arteries that supply the myocardium (the muscle of the heart) with oxygen and nutrients. It is sometimes also called coronary heart disease (CHD). Although CAD is the most common cause of CHD, it is not the only one. CAD is the leading cause of death worldwide. While the symptoms and signs of coronary artery disease are noted in the advanced state of disease, most individuals with coronary artery disease show no evidence of disease for decades as the disease progresses before the first onset of symptoms, often a "sudden" heart attack, finally arises. After decades of progression, some of these atheromatous plaques may rupture and (along with the activation of the blood clotting system) start limiting blood...

People who vape had worrisome changes in cardiovascular function, even as young adults

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metro heart and vascular :: Article Creator

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines | Circulation

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unstable microvascular angina :: Article Creator Vitamins By Condition Learn about User Reviews and read IMPORTANT information about user generated content Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from thi...

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets

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vertebral artery disease :: Article Creator Endovascular Treatment Of Vertebral Artery Stenosis Competing interests L. N. Hopkins has received research grants from Abbott Vascular, Boston Scientific, Cordis, ev3, and Toshiba. He has received Speaker's Bureau fees from Abbott Vascular and honoraria from Bard, Boston Scientific, Cordis, Complete Conference Management, Cleveland Clinic, and the Society for Cardiac Angiography and Interventions. He has a financial interest in AccessClosure, Boston Scientific, and Micrus and is a Consultant/member of the Advisory Board for Abbott Vascular, Access Closure, Bard, Boston Scientific, Cordis, Gore, Lumen Biomedical, Micrus, and Toshiba. Dr. Hopkins is also a Conference Director for Nurcon Conferences/Strategic Medical Seminars. M. J. Binning declares no competing interests.

People who vape had worrisome changes in cardiovascular function, even as young adults

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reduce stress and anxiety :: Article Creator Powerful Herbs For Stress And Anxiety Relief You Need To Try In today's fast-paced world, where stress and anxiety are prevalent, many individuals are turning to natural remedies to help alleviate these conditions. Among the various options, herbal solutions are gaining popularity for their potential to ease stress without the side effects commonly associated with pharmaceutical treatments. This article delves into the science behind these herbal remedies and highlights some of the most powerful herbs shown to offer relief from stress and anxiety. Understanding the science behind herbal remedies The pursuit of natural treatments for mental health has seen a significant rise in recent years. People are seeking alternative ways to manage stress and anxiety, with herbal remedies providing a compelling option. Unlike traditional medications, which may come with a range of side effects, herbs offer the ...