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destiny breast cancer trial :: Article Creator The Impact Of T-DXd In HER2-Positive Breast Cancer Tanya Gupta, MD, evaluates fam-trastuzumab deruxtecan-nxki and its role in breast cancer treatment. Tanya Gupta, MD, medical oncologist in the Stanford University Department of Medicine, Division of Medical Oncology, evaluates fam-trastuzumab deruxtecan-nxki (Enhertu; T-DXd) and its role in breast cancer treatment. T-DXd was granted accelerated approval from the FDA in 2019 for the treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who had received 2 or more prior HER2-targeted therapies in the metastatic setting. The approval was based on findings from the DESTINY-Breast01 trial (NCT03248492), a two-part, open-label, single-group, multicenter, phase 2 study in adult patients with pathologically documented HER2-positive metastatic breast cancer who had received previous treatment with ado-trastuzumab emtansine (T

oncology clinical trials :: Article Creator Study Reveals How Cancer Immunotherapy May Cause Myocarditis In Some Patients Just a moment... This request seems a bit unusual, so we need to confirm that you're human. Please press and hold the button until it turns completely green. Thank you for your cooperation! Press and Hold Press and hold the button If you believe this is an error, please contact our support team. 167.71.87.121 : 6a3a5f02-9728-4944-9c32-7a214854 Cell Therapy Biotechs Hunt For Autoimmune Expertise In Pivot From Oncology As cell therapy biotechs pivot from oncology to autoimmune disease, they face a big question: Can your cancer researchers run a lupus trial? Not necessarily, experts told BioSpace. And without the right teams in place, this segment of the biotech world may further put off potential investors to an area of innovation that is already facing a tough fundraising environment. "You

pilot clinical trial :: Article Creator Juryless Rape Trials Pilot Axed By Scottish Government Lawyers and judges expressed concern the plans could breach human rights laws A pilot scheme to hold trials for serious sexual offences without a jury has been scrapped by the Scottish government. The proposal would have seen a single judge decide whether people are guilty of rape and attempted rape in an attempt to increase conviction rates. The scheme was criticised by lawyers and judges who said it could breach human rights laws. Speaking at Holyrood, Justice Secretary Angela Constance said there was "not enough cross-party support" to go ahead with the plan, in what the Scottish Solicitors Bar Association called a "humiliating U-turn". However the government is going to press ahead with the abolition of the 'not proven' verdict, which has cross-party support. The juryless trial would have taken place

medidata imaging :: Article Creator Boehringer Taps Medidata E-clinical Tech For Another Five Years Boehringer Ingelheim was an early adopter of Medidata's electronic data collection (EDC) platform for clinical trials, and has now extended and expanded the contract. The new five-year alliance renews Boehringer's use of Medidata's Rave RDC toolkit, a cloud–based clinical data management system used to capture, manage, and report trial data, extending a collaboration that goes back more than seven years. It also signs the German pharma company up for myMedidata, a suite of patient-facing technologies aimed at enhancing patient centricity and diversity in decentralised clinical trials (DCTs), currently seeing an upsurge in adoption by the pharma industry. The web-based myMedidata patient portal provides access to electronic consent forms and electronic Clinical Outcome Assessment (eCOA) to capture patient experiences, as well as offer

leronlimab clinical trial :: Article Creator FDA Fires Broadside At CytoDyn Over COVID-19 Antibody Data In a rare move, the FDA has publicly accused US biotech CytoDyn of misrepresenting clinical trial results for leronlimab, an antibody being developed for COVID-19.  It's not uncommon for drug developers put a positive spin on lacklustre clinical data, but CytoDyn's attempts seems to have irritated the US regulator, specifically relating to its use of subgroup analyses to try to indicate a benefit for leronlimab. The biotech has run two studies to try to repurpose HIV and cancer candidate leronlimab as a COVID-19 therapy, neither of which achieved their primary objectives, but has said it will nevertheless file the data with regulators in countries including India and the Philippines. The 86-patient CD10 trial looked at the antibody's potential in mild-to-moderate COVID-19, but failed to show a benefit on any measures, including t

ptsd clinical trials near me :: Article Creator

emotional fatigue :: Article Creator Mental Exhaustion: 7 Symptoms And How To Recognize It Talking to a mental health professional or trusted friend can offer perspectives and solutions for managing overwhelming feelings. There are many issues with mental exhaustion nowadays. Work, family, and social life expectations can use up one's energy, leaving them feeling fatigued and stressed more often than not concerning their state of mind. What Is Mental Exhaustion? Mental tiredness, typically known as burnout, occurs when the brain is overstimulated and made to work very hard over an extended period. When mentally fatigued, people tend to feel like they cannot concentrate or make clear decisions like they usually do. The mind is empty of energy; unlike physical fatigue, where rest can help recover energy, mental fatigue sometimes persists even after taking some time off, thus impacting someone's emotional and cognitive health. S