Hypertension

vasospasm angina :: Article Creator Prinzmetal's Angina Prinzmetal's angina — also known as variant angina or angina inversa — occurs with coronary artery vasospasm resulting in myocardial ischemia. The smooth muscle in the coronary wall contracts without explanation, resulting in decreased blood flow to the myocardium which causes symptoms of angina. More common in young women, the etiology remains unclear. Symptoms usually occur at rest and are thought to be due to endothelial cell dysfunction. Coronary angiography will show normal coronary arteries (no atherosclerotic stenosis); however, the infusion of ergonovine can reproduce the spam. Ergonovine is not commonly used for this purpose any longer since the spasm can be severe and result in infarction. Coronary vasospasm can cause ST elevation on the ECG, but only during symptoms. Once the vasospasm resolves, the ECG changes will as well, making it...

scad coronary artery disease :: Article Creator The Slow, Powerful Work Of Bridging The Women's Health Gap PeopleImages.Com – Yuri A // Shutterstock The slow, powerful work of bridging the women's health gap When Carolyn Thomas suffered her first heart attack in 2008, she was in her fifties, a distance runner and as fit as can be. Yet the doctor in the ER diagnosed her with acid reflux, sent her home without treatment and told her she simply needed to rest.  "I felt so embarrassed for having made a big fuss over nothing that when my symptoms later returned, there was no way I was going back to that ER for help," Thomas, a PR manager in Victoria, Canada, told Reasons to be Cheerful.  Two weeks later, she had a massive heart attack that proved nearly fatal. The first doctor had not realized that Thomas was in the midst of a life-threatening health crisis. Men suffer heart diseases more frequently, but for women, they are ...

type 2 pulmonary hypertension :: Article Creator Tectonic Therapeutic Announces Positive Interim Data From Phase 1b Trial For TX45 In Patients With Group 2 Pulmonary Hypertension In HFpEF TX45 improved both left ventricular function and pulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension in Heart Failure with preserved Ejection Fraction ("PH-HFpEF"), supporting endpoints and patient population in ongoing APEX Phase 2 clinical trial Interim analysis demonstrated that TX45 achieved 17.9% reduction in Pulmonary Capillary Wedge Pressure ("PCWP") in the total study population of PH-HFpEF and >30% reduction in Pulmonary Vascular Resistance ("PVR") in Combined pre- and post-capillary PH ("CpcPH"), a subpopulation with more severe disease TX45 was well tolerated in patients with PH-HFpEF with no serious or severe adverse events, significant hypotension, or immune related reactions Company t...

coronary heart disease smoking :: Article Creator Muscle Fat May Pose Higher Risk To Heart Health Than Other Forms Of Fat Heart disease is the number one killer in the United States, causing one in five deaths. Several conditions, including high blood pressure, high blood cholesterol, diabetes, overweight and obesity increase a person's risk of heart disease. Research now suggests that how fat is distributed in the body, even in those of a healthy weight, could also affect heart disease risk. The study found that intramuscular fat, or fat contained within muscle tissue, increased the risk of serious heart disease, regardless of other risk factors. Traditionally viewed as a disease of affluence, heart disease is now common in low and middle-income countries, being responsible for one-third of all deaths globally. Lifestyle, and some health conditions, can increase or decrease a person's risk of developing heart disea...

anomalous right coronary artery surgery :: Article Creator

clinical research associates :: Article Creator Clinical Research Associate Clinical trial associates help conduct clinical trails that evaluate the safety and effectiveness of new treatment interventions or compare the effectiveness of new treatments to current best practices or other control groups. Clinical Research Associates & Coordinators affect every man, woman, and child in some way, whether now or in the future, as this type of research determines most options available for physicians to treat a patient. Clinical trials are required for every type of drug to treat every type of disease. In many medical settings, three types of clinical trials are usually conducted. These are called Phase I, Phase II, and Phase III trials and are administered in sequence to learn more about a given treatment intervention. Several steps or phases of clinical research must occur before a large-scale Phase III study is implemented. A Phase IV tria...