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Showing posts from February, 2025

The Predictive Value of Carotid Ultrasonography With Cardiovascular Risk Factors—A “SPIDER” Promoting Atherosclerosis

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crispr trials :: Article Creator Creating The World's First CRISPR Medicine, For Sickle Cell Disease When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes. "The encounter made me wonder, couldn't we do more for these patients?" said Sankaran, who is now the HMS Jan Ellen Paradise, MD Professor of Pediatrics at Boston Children's Hospital. Get more HMS news As a budding hematologist, Sankaran knew all too well that people with sickle cell disease — marked by malformed, sickle-shaped red blood cells that can aggregate and block small vessels — experience excruciating pain crises, tissue and organ damage, and shortened life expectancy. He also understood that the only treatment available at the time was hydroxyurea, which reduces sickling but isn't effec...

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines | Circulation

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chronic illness and ptsd :: Article Creator Many Aging Vietnam War Vets Are Still Battling PTSD, Along With Chronic Illnesses, That Combat Exposure May Make More Likely, New Research Finds Two groundbreaking studies shed light on combat's lasting physical and psychological damage more than 50 years on. The toll of combat exposure and post-traumatic stress disorder (PTSD) is still disrupting the lives of soldiers who returned from Vietnam more than a half-century ago, according to two studies that followed and checked in with the same men — fewer than 0.4% of U.S. Military there were women — over 35 years. Among the most striking findings: Soldiers who saw combat in the 1960s and '70s were nearly twice as likely to have a diagnosed heart condition in 2020 compared to vets in noncombat roles. And veterans with heart disease reported significantly more comorbid chronic illnesses like arthritis and respiratory conditions, including sleep apnea...

2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation

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things that are good for your heart :: Article Creator 9 Ways To Take Care Of Your Heart Health For Valentine's Day Heart disease remains the leading cause of death in the US, according to the American Heart Association's 2025 Heart Disease and Stroke Statistics Update. In the US, someone dies of cardiovascular disease every 34 seconds. The association states that though medical advances have helped people with cardiovascular diseases live longer, risk factors like high blood pressure and obesity continue to grow at "alarming rates." While your family history and age can increase your risk, there are preventable risk factors. To reduce your risk of heart disease, there are habits you can incorporate into your lifestyle. 1. Take a daily walk Decades of research support cardiovascular exercise as a first defense against heart disease. Walking is an easy, simple way to get cardio exercise in, and you can do it pretty much anywhere outdo...

Lower extremity arterial disease in patients with diabetes: a contemporary narrative review

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whitney dafoe cfs :: Article Creator A Geneticist's Quest To Understand His Son's Mysterious Disease About 10 years ago, Stanford University genomicist Ronald W. Davis began a new investigation into a mysterious disease that had disabled his son, Whitney Dafoe. A photographer and avid traveller in his 20s, Dafoe could no longer care for himself. He slowly lost the ability to eat and eventually even to speak. He visited doctors for years before he finally found one who could diagnose him with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) based on his strange constellation of symptoms. But with the diagnosis, Dafoe and his family soon learned that little research had been done on the disease, and there was no treatment. Davis decided to do what he could to fill that gap. Davis's first step was to set up a centrifuge in the tool shed in his backyard. When he got home from his job as director of the Stanford Genome Technology...

Kawasaki Disease: Practice Essentials, Background, Pathophysiology

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middle cerebral artery infarction :: Article Creator T. Dorina Papageorgiou Lab Content The T. Dorina Papageorgiou - Investigational Targeted Brain Neurotherapeutics Lab has developed a novel, targeted and individualized MRI-compatible brain computer interface (BCI) based on associative learning principles that can induce neuromodulation in patients with neurological sequelae following stroke (commonly a result of a posterior cerebral artery infarct, or a middle cerebral artery infarct), traumatic brain injury or tumor resection. We call our MRI-BCI, individualized real-time functional MRI neurofeedback (iRTfMRI nFb), which is based on promoting the reorganization of networks by bypassing lesioned pathways and capitalizing on redundant, intact but functionally associated pathways to the injured ones. This is achieved by modulating the magnitude and spatial extent of Blood-Oxygen-Level-Dependent (BOLD) signal with the goal to recover the brai...

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines | Circulation

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heart scan :: Article Creator Local Resident Shares Heart Scan Journey 72-year-old LuAnn Lamie is retired art teacher who underwent open heart surgery less than a month ago. LAFAYETTE, Ind. (WLFI) — "When people say I'm so surprised you had open heart surgery, I'm like if you're surprised, think how I feel." 72-year-old LuAnn Lamie is retired art teacher who underwent open heart surgery less than a month ago. With having no other symptoms other than being tired, she received a heart scan at Franciscan Health.  "My primary care person said, 'LuAnn, you know with your age and the fact you take statins and cholesterol medicine perhaps you should try one of these scans,'" said Lamie.  Through the heart scan results, LuAnn found out she has three blockages in her chest and an aortic valve that was leaking. "I had no idea of any of this," Lamie said.  LuAnn credits some of her recovery ...

The Predictive Value of Carotid Ultrasonography With Cardiovascular Risk Factors—A “SPIDER” Promoting Atherosclerosis

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non invasive coronary angiography :: Article Creator Current State Of Non-Invasive Coronary MSCT Angiography 1. Schuijf JD, Bax JJ, Shaw LJ et al.: Meta-analysis of comparative diagnostic performance of magnetic resonance imaging and multislice computed tomography for non-invasive coronary angiography. Am Heart J 2006; 151: 404–11. MEDLINE 2. Kopp AF, Ohnesorge B, Flohr T et al.: Multidetektor-CT des Herzens: Erste klinische Anwendung einer retrospektiv EKG-gesteuerten Spirale mit optimierter zeitlicher und örtlicher Auflösung zur Darstellung der Herzkranzgefäße. Rofo 2000; 172: 429–35. MEDLINE 3. Flohr T, Stierstorfer K, Raupach R et al.: Peformance evaluation of a 64-slice CT system with z-flying spot. Rofo 2004; 176: 1803–10. MEDLINE 4. Flohr TG, McCollough CH, Bruder H et al.: First performance evaluation of a dual-source CT (DSCT) system. Eur Radiol 2006; 16: 256–68. MEDLINE 5. Achenbach S, Ropers D, Kuettner A et al.: Contrast-enha...