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Early Type 2 Diabetes Treatment Prolongs Life - Study

Research showed early treatment of type 2 diabetes with drugs such as metformin reduced the risk of future complications

Treating type 2 diabetes patients as early as possible can prolong life and reduce the risk of future complications, according to research.

Scientists from the Universities of Oxford and Edinburgh analysed data spanning more than four decades from the UK Prospective Diabetes Study (UKPDS) - one of the longest type 2 diabetes clinical trials.

The findings showed controlling blood glucose early with insulin and drugs led to 10% fewer deaths as well as reducing the risk of things such as heart attacks, kidney failure and vision loss.

Type 2 diabetes, which makes up the majority of diabetes cases, occurs when a person's cells no longer respond to insulin produced by the pancreas, meaning the body cannot regulate blood sugar levels.

Professor Rury Holman, the founding director of the University of Oxford Diabetes Trials Unit and chief investigator of the UKPDS, said the findings were "remarkable" and showed the importance of early diagnosis.

The UKPDS trial began in 1977, where newly-diagnosed type 2 diabetes patients were assigned to either intensive or conventional blood glucose control strategy.

The intensive strategy involved using sulfonylurea - tablets that stimulate cells to make more insulin - insulin therapy, or metformin therapy, a drug which helps the insulin that the body produces to work better.

The standard method involved making changes to diet.

'Crucial'

The findings showed that, compared with diet, controlling blood glucose with sulfonylurea, insulin, or metformin had a lifelong reduced risk of early death and heart attack.

Guidelines were later changed worldwide to recommend these intensive therapies for everyone with type 2 diabetes.

Professor Amanda Adler, director of the Diabetes Trial Unit, said it showed early treatment of type 2 diabetes was "crucial".

"Playing catch-up with blood glucose control is not sufficient," she said.

DBD Chapter 34 PTB Release Date And All Killer Leaks So Far

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Dead By Daylight is set to receive its final episode of 2024 in a couple of months. We've had some excellent crossovers throughout the year, but BeHaviour's finale is set to be an original. Here you will find the DBD Chapter 34 PTB release date along with all of the leaks so far that have possibly revealed the original killer.

Before the next chapter arrives, there is plenty else for Dead By Daylight fans to anticipate. The October 2024 roadmap reveals this year's Haunted By Daylight is set for October 17th, and some new limited-time rewards have leaked for DBD Day. In addition, we have 2v8 mode set to return in November for a very brief period, and BeHaviour has confirmed that a perk is getting buffed following update 8.3.0.

While the Halloween event and return of 2v8 are both very exciting, there is also the looming launch of Chapter 34. The PTB release date has possibly leaked along with revealing details about the killer.

Dead By Daylight Chapter 34 PTB release date

Per renowned leaker Dvveet, the expected release date for the Dead By Daylight Chapter 34 PTB is November 12th.

The full episode should then arrive on all platforms by December 3rd. Of course, as per usual, the PTB will only be playable on PC through Steam.

It's important to note that neither date has been confirmed as of writing. Assuming the leak is correct, then the public-test build will start at the exact same time 2v8 returns.

Dead By Daylight Chapter 34 killer leaks

Leaks originally claimed that the Dead By Daylight Chapter 34 killer is female. This would make sense seeing as there's been a female killer every year since 2020, and so far we haven't had one for 2024.

There has been some mixed messages about the killer, but it appears they are female and that they do come with a pet dog. Original leaks claimed she was a bounty hunter, but it's unknown if this is still the case as there were supposedly some potential controversies with the lore.

Although nothing is official as of writing, concept art for the character has possibly leaked online. Shared on the DBDLeaks Discord, the concept art shows a fairly old woman with a dog by her side.

Lastly, in addition to leaked concept art, it's claimed that the killer is called The Hellion. We can't share the leaked concept art here, but you can check out it in a video from Schmuckles embedded below:

Alongside the killer there will be a new survivor and map. However, nothing about these components has leaked as of writing.

For more Dead By Daylight, check out our guide to the best expansions.

Dead by Daylight

Platform(s): Google Stadia, Nintendo Switch, PC, PlayStation 4, PlayStation 5, Xbox One, Xbox Series X

Genre(s): Action, Survival Horror

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Cardiovascular Risk Factors In Patients With Type 2 Diabetes In Germany

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