Exercise capacity in COPD patients with exercise-induced pulmonary hypertension
Ingunn Skjørten, 1,2 Janne Mykland Hilde, 3 Morten Nissen Melsom, 1 Jonny Hisdal, 4 Viggo Hansteen, 5 Kjetil Steine, 2,3 Sjur Humerfelt 6 1 Department of Pulmonary Medicine, LHL Hospital Gardermoen, Jessheim, 2 Faculty of Medicine, University of Oslo, Oslo, 3 Department of Cardiology, Akershus University Hospital, Lørenskog, 4 Section of Vascular Investigations, Oslo University Hospital-Aker, 5 Department of Cardiology, Oslo University Hospital-Aker, 6 Clinic of Allergology and Respiratory Medicine, Oslo, Norway Background : Pulmonary hypertension (PH) in patients with COPD is associated with reduced exercise capacity. A subgroup of COPD patients has normal mean pulmonary artery pressure (mPAP) at rest, but develops high mPAP relative to cardiac output (CO) during exercise, a condition we refer to as exercise-induced pulmonary hypertension (EIPH). We hypothesized that COPD patients with EIPH could be identified by cardiopulmonary exercise test (CPET) and that these patients ha...