Afib: Causes, Symptoms, and Treatment Options



home remedies for lowering blood pressure :: Article Creator

How To Control High Blood Pressure At Home If It Spikes Suddenly

High blood pressure, also known as hypertension, can be a serious condition that requires immediate attention, especially if it spikes suddenly. Rapid increases in blood pressure can pose risks to your heart, brain, and overall health. Understanding how to manage and control these spikes at home can be crucial in preventing more severe health issues. Here's a detailed guide on how to handle a sudden rise in blood pressure effectively.

Immediate Steps to TakeCalm the IndividualFind a Quiet Space: If someone's blood pressure suddenly spikes, the first step is to have them sit down in a calm, quiet environment. Avoid any bustling or noisy surroundings that might exacerbate the stress.Encourage Deep Breathing: Have the individual take slow, deep breaths. Deep breathing can help relax the body and mind, which may assist in lowering the blood pressure.

Hydrate ProperlyProvide Room Temperature Water: Offer the person a glass of room temperature water. They should sip it slowly, as rapid consumption might not be as effective. Proper hydration can help with blood pressure regulation.

Monitor SymptomsCheck for Other Symptoms: Besides high blood pressure, be observant of other symptoms like severe headaches, chest pain, shortness of breath, or vision changes. These could indicate a more serious condition. Dietary and Natural RemediesConsume Beneficial FruitsBananas: High in potassium, bananas can help manage blood pressure levels. Potassium helps balance sodium levels in the body, which is essential for maintaining healthy blood pressure.Kiwi: Rich in vitamins and antioxidants, kiwi can aid in reducing blood pressure. It helps improve blood vessel health and can be a good addition to the diet.Apples: Apples contain fiber and potassium, which can help control blood pressure levels. Eating an apple may provide a temporary relief in blood pressure spikes. Use Lemon WaterPrepare Lemon Water: Lemon water is known for its hydrating and soothing effects. Squeeze half a lemon into a glass of water and have the person drink it slowly. Avoid adding salt or sugar.Increase Water Intake: Drinking a couple of glasses of water can help flush out excess sodium and reduce blood pressure. This also promotes better hydration and overall health. Additional Measures for Immediate ReliefApply Water to FaceCool Compress: Gently splash cool water on the person's face. This can have a calming effect and may help lower blood pressure levels temporarily. Get Fresh AirGo for a Walk: If possible, take a short, gentle walk in a well-ventilated area. Fresh air and light physical activity can be beneficial in managing high blood pressure. Long-Term Strategies for Blood Pressure ManagementIncorporate Regular ExerciseDaily Physical Activity: Engage in regular physical activities such as walking, jogging, or yoga. Aim for at least 30 minutes of exercise most days of the week. Regular exercise strengthens the heart and helps regulate blood pressure. Manage StressReduce Stress: Practice stress management techniques such as meditation, deep breathing exercises, or mindfulness. Chronic stress can contribute to elevated blood pressure, so managing it effectively is crucial. Follow a Balanced DietReduce Sodium Intake: Limit the amount of salt in your diet. Opt for fresh, whole foods and avoid processed foods that are high in sodium.Increase Potassium-Rich Foods: Incorporate foods high in potassium, such as leafy greens, bananas, and avocados, into your diet. Potassium helps balance blood pressure levels. Monitor Blood Pressure RegularlyRegular Check-Ups: Use a home blood pressure monitor to keep track of your readings regularly. Monitoring your blood pressure can help you and your healthcare provider make informed decisions about managing your condition. Consult with a Healthcare ProfessionalSeek Medical Advice: If high blood pressure persists or if you experience any severe symptoms, it's important to consult with a healthcare professional. They can provide personalized advice and treatment options. Managing a sudden spike in blood pressure at home involves immediate steps to calm the individual, hydrate properly, and use natural remedies. Implementing long-term strategies like regular exercise, stress management, and a balanced diet is also essential for overall blood pressure control. Always consult with a healthcare professional if you have persistent issues or experience severe symptoms. Taking proactive steps to monitor and manage your blood pressure can significantly reduce health risks and improve your quality of life. Five Unexpected Seeds That Pack Protein Punch and Why You Should Add Them to Diet What Happens When You Drink Tulsi Water Every Day? Find Out! How to Avoid This Mistake While Sleeping at Night to Prevent Regret

Novel Low-dose 3-in-1 Blood Pressure Pill Significantly Outperforms Standard Care, Study Shows

New research shows that a treatment plan based on a novel combination of low doses of three anti-hypertensive drugs in a single pill—known as GMRx2—was superior to a high-quality standard care treatment plan at lowering blood pressure in patients with uncontrolled hypertension.

Results of the 'deliVERy of Optimal blood pressure coNtrol in afrICA (VERONICA)-Nigeria' trial, led by The George Institute for Global Health, were presented today at the European Society of Cardiology Congress 2024 and simultaneously published in the Journal of the American Medical Association (JAMA).

The GMRx2 treatment plan involved a once daily pill containing telmisartan, amlodipine and indapamide at a quarter, half or standard doses. The standard care treatment plan recommended by the Nigerian Ministry of Health began with monotherapy, followed by dual and triple combination therapy, and was typical of hypertension guidelines for many countries.

After 6 months treatment, home systolic blood pressure was 31mmHg lower in the GMRx2 group compared to 26 mmHg lower with standard care—the 5.8 mmHg difference was highly clinically and statistically significant. Existing evidence shows that with every 5 mmHg reduction in systolic blood pressure there is a 10% reduction in major cardiovascular events such as stroke, heart attack and heart failure.

After just one month, 81% of participants in the GMRx2 group achieved clinic-measured blood pressure control versus 55% with standard care. This improvement was sustained at six months with 82% achieving control, compared with 72% under standard care. Tolerability of both treatment plans was good, with no withdrawals due to adverse events.

Prof Dike Ojji, Head of the Cardiovascular Research Unit at the University of Abuja, Nigeria and study principal investigator said, "The triple pill still produced clinically meaningful reductions in blood pressure compared to standard care, even when standard care closely followed current guidelines and involved more clinic visits."

"In low-income countries, fewer than one in four treated people achieve blood pressure control and in high-income settings it is only between 50% and 70%," added Prof Ojji. "So to see rates of over 80% in just one month is impressive."

It is estimated that over a billion adults live with hypertension worldwide, with two-thirds living in low- and middle-income countries. High blood pressure is the leading risk factor for mortality, accounting for 10.8 million deaths a year. It is hoped this new treatment could have a big impact on reducing rates of cardiovascular disease, particularly in countries with the highest burden.

GMRx2 is the leading drug candidate of George Medicines, a late-stage, biopharmaceutical company addressing significant unmet need in the treatment of cardiometabolic disease, established to commercialize the research of The George Institute for Global Health. Earlier this month, GMRx2 was submitted to the US Food and Drug Administration (FDA) for the treatment of hypertension.

Phase III data from two additional GMRx2 trials were also presented at the congress, showing good tolerability and clinically relevant blood pressure reductions compared to placebo and dual combination therapy.

Prof Anthony Rodgers, Senior Professorial Fellow at The George Institute and Chief Medical Officer at George Medicines said, "Our mission is to develop sustainable solutions that can improve the health of millions of people worldwide and alleviate strain on health systems. There is a global goal to reach 80% blood pressure control among those treated, but no country has yet achieved this. With the VERONICA trial, we've shown the potential of this novel strategy to reach this ambitious target."

"There has been little innovation in this field, so it's rewarding to see many years of research by The George Institute culminate in a novel treatment using established medicines to address an unmet need," he added.

More information: Comparison of Low-Dose Triple Pill and Standard Care Protocols for Hypertension Treatment in Black Africans in Nigeria: A Randomized Clinical Trial, JAMA (2024). DOI: 10.1001/jama.2024.18080

Citation: Novel low-dose 3-in-1 blood pressure pill significantly outperforms standard care, study shows (2024, August 31) retrieved 4 September 2024 from https://medicalxpress.Com/news/2024-08-dose-blood-pressure-pill-significantly.Html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.


3 In 1 Pill Revolutionizing Blood Pressure Control

A treatment strategy utilizing a novel combination of three anti-hypertensive drugs at low doses in a single pill—referred to as GMRx2—was more effective at reducing blood pressure in patients with uncontrolled hypertension compared to a high-quality standard care approach. The findings from the 'deliVERy of Optimal blood pressure coNtrol in afrICA (VERONICA)-Nigeria' trial, led by The George Institute for Global Health, were unveiled today at the European Society of Cardiology Congress 2024 and concurrently published in the Journal of the American Medical Association (JAMA).(1✔ ✔Trusted SourceLow-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria A Randomized Clinical Trial 3-in-1 blood pressure pill developed from George Institute research achieves major milestoneGo to source) GMRx2: A Game-Changer in Hypertension Treatment The GMRx2 regimen involved a once-daily pill containing telmisartan, amlodipine, and indapamide at quarter, half, or full doses. The standard care approach, as recommended by the Nigerian Ministry of Health, began with monotherapy and progressed to dual and triple combination therapy, aligning with hypertension guidelines in many countries. 'Over 80% of patients achieved blood pressure control within just one month using GMRx2. #hypertension #globalhealth #medindia' After 6 months treatment, home systolic blood pressure was 31mmHg lower in the GMRx2 group compared to 26 mmHg lower with standard care – the 5.8 mmHg difference was highly clinically and statistically significant. Existing evidence shows that with every 5 mmHg reduction in systolic blood pressure there is a 10% reduction in major cardiovascular events such as stroke, heart attack and heart failure.

After just one month, 81% of participants in the GMRx2 group achieved clinic-measured blood pressure control versus 55% with standard care. This improvement was sustained at six months with 82% achieving control, compared with 72% under standard care. Tolerability of both treatment plans was good, with no withdrawals due to adverse events.

Prof Dike Ojji, Head of the Cardiovascular Research Unit at the University of Abuja, Nigeria and study principal investigator said, "The triple pill still produced clinically meaningful reductions in blood pressure compared to standard care, even when standard care closely followed current guidelines and involved more clinic visits."

"In low-income countries fewer than one in four treated people achieve blood pressure control and in high-income settings it is only between 50% and 70%," added Prof Ojji, "so to see rates of over 80% in just one month is impressive."

It is estimated that over a billion adults live with hypertension worldwide, with two-thirds living in low- and middle-income countries.4 High blood pressure is the leading risk factor for mortality, accounting for 10.8 million deaths a year.4,5 It is hoped this new treatment could have a big impact on reducing rates of cardiovascular disease, particularly in countries with the highest burden.

Advertisement

Triple Pill Regimen Shows Superior Results GMRx2 is the leading drug candidate of George Medicines, a late-stage, biopharmaceutical company addressing significant unmet need in the treatment of cardiometabolic disease, established to commercialise the research of The George Institute for Global Health. Earlier this month, GMRx2 was submitted to the US Food and Drug Administration (FDA) for the treatment of hypertension.

Phase III data from two additional GMRx2 trials were also presented at the congress, showing good tolerability and clinically relevant blood pressure reductions compared to placebo and dual combination therapy.

Advertisement

Prof Anthony Rodgers, Senior Professorial Fellow at The George Institute and Chief Medical Officer at George Medicines said, "Our mission is to develop sustainable solutions that can improve the health of millions of people worldwide and alleviate strain on health systems. There is a global goal to reach 80% blood pressure control among those treated, but no country has yet achieved this. With the VERONICA trial, we've shown the potential of this novel strategy to reach this ambitious target."

"There has been little innovation in this field, so it's rewarding to see many years of research by The George Institute culminate in a novel treatment using established medicines to address an unmet need," he added.

References:

  • Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria A Randomized Clinical Trial - (https://jamanetwork.Com/journals/jama/fullarticle/2823291 /)
  • Source-Eurekalert






    Comments

    Popular Posts

    Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

    Effects of hot weather, humidity on blood pressure, heart

    High blood pressure warning - the age you should definitely get checked for hypertension - Express